Investigating the role of glycans in biological processes
Chemoenzymatic glycan editing for deciphering biological functions of glycans
['FUNDING_OTHER'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-11011466
This study is looking at how certain sugars on the surface of our cells affect how they behave, and by changing these sugars in a special way, researchers hope to learn more about their role in health and diseases, which could help develop new treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11011466 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how cell-surface glycans, which are crucial for various biological functions, interact and influence cellular behavior. By utilizing advanced techniques like chemoenzymatic glycan editing, researchers aim to modify and study these glycans in their natural environments. This approach allows for precise manipulation of glycan structures, providing insights into their roles in health and disease. Patients may benefit from a better understanding of how glycan abnormalities contribute to diseases, potentially leading to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions linked to glycan abnormalities, such as certain cancers or autoimmune diseases.
Not a fit: Patients without any known glycan-related disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to novel treatments for diseases associated with abnormal glycosylation.
How similar studies have performed: Previous research using similar glycan editing techniques has shown promising results in understanding glycan functions, indicating a strong potential for success in this area.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WU, PENG — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: WU, PENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.