Investigating the role of GATA transcription factors in endometriosis
Official title: Roles of GATA Transcription Factors in Endometriosis
Funded at Northwestern University at Chicago · NIH-11026433 · Data updated 2026-11-12
This study is looking at how certain proteins in the body change in women with endometriosis compared to those without, to help us understand more about how this condition develops and continues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | February 5, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $652,138 |
| NIH project number | 5R01HD113891-02 |
| Project ID | NIH-11026433 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women of childbearing age who have been diagnosed with endometriosis.
✕Less likely to help
Patients who do not have endometriosis or are outside the childbearing age may not benefit from this research.
What this research studies
This research focuses on understanding the molecular mechanisms behind endometriosis, a condition affecting many women. It examines how GATA transcription factors, which are crucial for normal endometrial function, change in women with endometriosis. By analyzing tissue samples from both endometriosis-affected and unaffected women, the study aims to uncover differences in gene expression and chromatin organization. This could lead to a better understanding of how endometriosis develops and persists.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for women suffering from endometriosis.
How similar studies have gone: Previous research has shown promising results in understanding the molecular basis of endometriosis, but this specific approach focusing on GATA transcription factors is relatively novel.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Chakravarti, Debabrata — Northwestern University at Chicago
- Study coordinator: Chakravarti, Debabrata
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.