Investigating the role of galectin-8 in melanoma progression
Analysis of galectin-8 and its ligands in melanoma progression
This study is looking at how a protein called galectin-8 affects the growth of melanoma, a type of skin cancer, and how it might help us find better treatments for patients like you by analyzing the sugars on cancer cells.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida International University NIH-funded |
| Lab location | 1 site (Miami, United States) |
| Project ID | NIH-11090387 on NIH RePORTER |
What this research studies
This research focuses on understanding how galectin-8 and its ligands contribute to the progression of metastatic melanoma. The team will analyze the glycan structures on melanoma cells and how they interact with galectin-8, which may influence tumor behavior and resistance to therapies. By identifying specific biomarkers and therapeutic targets, the research aims to improve treatment outcomes for patients with melanoma. Patients may be involved in providing samples or data to help elucidate these mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with metastatic melanoma who are undergoing or considering immune checkpoint inhibition therapy.
Not a fit: Patients with early-stage melanoma or those who do not have a diagnosis of melanoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved predictive biomarkers and novel treatment strategies for patients with metastatic melanoma.
How similar studies have performed: Other research has shown promising results in targeting glycan interactions in cancer therapy, suggesting that this approach may yield significant insights.
Where this research is happening
Miami, United States
- Florida International University — Miami, United States (Active)
Researchers
- Principal investigator: Dimitroff, Charles J — Florida International University
- Study coordinator: Dimitroff, Charles J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.