Investigating the role of fat tissue in heart rhythm disorders
Trans-omic analysis of epicardial adipose tissue in atrial fibrillation
This study is looking at how the fat around the heart affects atrial fibrillation, a common heart rhythm problem, to find new ways to prevent and treat it, especially for people from different backgrounds.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10764794 on NIH RePORTER |
What this research studies
This research focuses on understanding how epicardial adipose tissue (fat surrounding the heart) influences atrial fibrillation (AF), a common heart rhythm disorder. By analyzing the metabolic and molecular characteristics of this fat tissue, researchers aim to identify new targets for preventing and treating AF. The study will involve collecting tissue samples and using advanced techniques to explore the relationship between fat tissue and heart function, particularly in patients with different racial and ethnic backgrounds. This approach may lead to personalized treatment strategies based on individual patient profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with atrial fibrillation, particularly those who are obese or have significant epicardial adipose tissue.
Not a fit: Patients without atrial fibrillation or those who do not have significant fat tissue around the heart may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment options for patients with atrial fibrillation.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between adipose tissue and heart conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Goldberger, Jeffrey J — University of Miami School of Medicine
- Study coordinator: Goldberger, Jeffrey J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.