Investigating the role of CRACD in small cell lung cancer
Official title: CRACD-controlled cell plasticity and small cell lung cancer
Funded at University of Tx Md Anderson Can Ctr · NIH-11004360 · Data updated 2026-11-12
This study is looking at small cell lung cancer to learn more about a gene called CRACD that might help explain how this cancer grows and responds to treatments, with the hope of finding better, personalized therapies for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $542,413 |
| NIH project number | 5R01CA278967-02 |
| Project ID | NIH-11004360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with small cell lung cancer, particularly those who have not responded well to current therapies.
✕Less likely to help
Patients with other types of lung cancer or those whose SCLC is in a very advanced stage may not benefit from this research.
What this research studies
This research focuses on small cell lung cancer (SCLC), a highly aggressive form of cancer with limited treatment options. The project aims to understand the genetic mutations that drive SCLC, particularly the role of the CRACD gene, which is often altered in SCLC tumors. By studying how CRACD affects tumor growth and response to therapies, researchers hope to identify new biomarkers and potential treatment strategies. Patients may benefit from insights that could lead to more effective therapies tailored to their specific cancer profiles.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options and improved outcomes for patients with small cell lung cancer.
How similar studies have gone: Previous research has shown promise in targeting genetic mutations in cancer, suggesting that this approach could yield significant advancements in treatment for SCLC.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Park, Jae-Il — University of Tx Md Anderson Can Ctr
- Study coordinator: Park, Jae-Il
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.