Investigating the role of CRACD in small cell lung cancer

CRACD-controlled cell plasticity and small cell lung cancer

['FUNDING_R01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-11004360

This study is looking at small cell lung cancer to learn more about a gene called CRACD that might help explain how this cancer grows and responds to treatments, with the hope of finding better, personalized therapies for patients like you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded)
Locations1 site (HOUSTON, UNITED STATES)
Trial IDNIH-11004360 on ClinicalTrials.gov

What this research studies

This research focuses on small cell lung cancer (SCLC), a highly aggressive form of cancer with limited treatment options. The project aims to understand the genetic mutations that drive SCLC, particularly the role of the CRACD gene, which is often altered in SCLC tumors. By studying how CRACD affects tumor growth and response to therapies, researchers hope to identify new biomarkers and potential treatment strategies. Patients may benefit from insights that could lead to more effective therapies tailored to their specific cancer profiles.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with small cell lung cancer, particularly those who have not responded well to current therapies.

Not a fit: Patients with other types of lung cancer or those whose SCLC is in a very advanced stage may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatment options and improved outcomes for patients with small cell lung cancer.

How similar studies have performed: Previous research has shown promise in targeting genetic mutations in cancer, suggesting that this approach could yield significant advancements in treatment for SCLC.

Where this research is happening

HOUSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.