Investigating the role of a specific receptor in fat metabolism
Sigmar1 in lipid metabolism
This study is looking at how a specific receptor in the body affects fat storage and energy use, especially in people dealing with obesity, to help find better ways to manage related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project ID | NIH-10534192 on NIH RePORTER |
What this research studies
This research focuses on understanding how the Sigma-1 receptor (Sigmar1) influences lipid metabolism, particularly in the context of obesity. By studying genetically modified mouse models, the researchers aim to uncover the receptor's role in regulating fat storage and energy production in the heart and other organs. The study examines how disruptions in this receptor's function may lead to metabolic diseases and associated complications. Patients may benefit from insights gained into how to better manage conditions related to obesity and lipid metabolism.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include adults with obesity or metabolic disorders.
Not a fit: Patients without obesity or metabolic disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating metabolic diseases linked to obesity.
How similar studies have performed: Previous research has shown promising results in understanding lipid metabolism through similar molecular approaches, indicating potential for success.
Where this research is happening
Shreveport, United States
- Louisiana State Univ Hsc Shreveport — Shreveport, United States (Active)
Researchers
- Principal investigator: Bhuiyan, Md. Shenuarin — Louisiana State Univ Hsc Shreveport
- Study coordinator: Bhuiyan, Md. Shenuarin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.