Investigating the role of a specific protein in ovarian cancer
Role of protein kinase ADCK5 in ovarian cancer
This study is looking at how a protein called ADCK5 affects the growth of ovarian cancer and why some treatments might not work, with the goal of finding better ways to help patients with ovarian cancer live longer and healthier lives.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore County NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10725728 on NIH RePORTER |
What this research studies
This research focuses on understanding how the protein kinase ADCK5 influences ovarian cancer progression and treatment resistance. By examining the genetic factors associated with ADCK5, researchers aim to identify new therapeutic targets that could improve treatment outcomes for patients with ovarian cancer. The study will analyze the relationship between ADCK5 expression and patient survival, particularly in those with specific genetic mutations. This could lead to more effective treatment strategies for patients facing this challenging disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with ovarian cancer, especially those with p53 mutations.
Not a fit: Patients with early-stage ovarian cancer or those without p53 mutations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve survival rates for ovarian cancer patients, particularly those with drug-resistant forms of the disease.
How similar studies have performed: Previous research has shown promising results in targeting genetic factors in cancer treatment, suggesting that this approach may yield beneficial outcomes.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore County — Baltimore, United States (Active)
Researchers
- Principal investigator: Padmanabhan, Achuth — University of Maryland Baltimore County
- Study coordinator: Padmanabhan, Achuth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.