Investigating the role of a specific protein in female ovulation and fertility.
The Role of FOS in the Ovary
This study is looking at how a protein called FOS affects ovulation and the development of a structure in the ovaries that helps with fertility, and it's for anyone interested in understanding more about female reproductive health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10816373 on NIH RePORTER |
What this research studies
This research focuses on understanding how the FOS protein influences ovulation and the formation of the corpus luteum, which are critical processes for female fertility. By studying both human and mouse models, the research aims to uncover the mechanisms by which FOS regulates gene expression during these reproductive events. The approach includes analyzing the effects of gonadotropins on FOS expression and its role in ovarian function, which could lead to new insights into fertility regulation.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing difficulties with ovulation or fertility.
Not a fit: Patients who are not seeking to conceive or have no fertility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for women facing fertility issues.
How similar studies have performed: Previous studies have shown that understanding transcription factors like FOS can significantly impact fertility research, indicating potential for success in this area.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Jo, Misung — University of Kentucky
- Study coordinator: Jo, Misung
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.