Investigating the role of a specific enzyme in colon inflammation and cancer
Role for myeloid acid ceramidase in colon inflammation and cancer
This study is looking at how a specific enzyme called acid ceramidase affects inflammation and cancer in the colon, and it hopes to find new ways to treat these issues that could help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-11085972 on NIH RePORTER |
What this research studies
This research focuses on understanding how a particular enzyme, acid ceramidase, influences inflammation and cancer in the colon. By studying both animal models and human tissues, the researchers aim to determine if targeting this enzyme can provide new anti-inflammatory and anti-cancer therapies. The project utilizes advanced techniques to manipulate and observe the effects of this enzyme in immune cells and its role in colitis and colon cancer. Patients may benefit from insights that could lead to innovative treatments for these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from colitis or those at risk for colon cancer.
Not a fit: Patients with conditions unrelated to colon inflammation or cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that reduce inflammation and prevent colon cancer.
How similar studies have performed: Other research has shown promising results in targeting similar enzymes for therapeutic purposes, suggesting potential for success in this approach.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Snider, Ashley Jones — University of Arizona
- Study coordinator: Snider, Ashley Jones
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.