Investigating the role of a specific brain system in Parkinson's disease
The Pallidohabenular System in Parkinsonism
This study is looking at how a specific group of brain cells affects mood and movement in people with Parkinson's disease, hoping to find new ways to help manage the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11006266 on NIH RePORTER |
What this research studies
This research focuses on understanding how a particular group of neurons in the brain, known as the pallidohabenular system, functions in relation to Parkinson's disease. By examining the connections and signaling of these neurons, the study aims to uncover how they may influence mood and movement in patients with this condition. The researchers will utilize advanced techniques to analyze the synaptic connectivity and neurotransmitter activity in both healthy and parkinsonian states. This could provide insights into the underlying mechanisms of Parkinson's and potentially lead to new therapeutic approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who may experience mood disturbances or motor function issues.
Not a fit: Patients with Parkinson's disease who do not exhibit mood disturbances or those with other unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for mood and movement disorders associated with Parkinson's disease.
How similar studies have performed: Previous research has shown promising results in understanding the basal ganglia's role in movement and mood regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Smith, Yoland — Emory University
- Study coordinator: Smith, Yoland
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.