Investigating the role of a protein in melanoma development and progression
Role of sirtuin 6 in melanoma development and progression
This study is looking at how a protein called SIRT6 affects the growth and spread of melanoma, a serious skin cancer, to find new ways to treat it better for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wm S. Middleton Memorial Veterans Hosp NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11183334 on NIH RePORTER |
What this research studies
This research focuses on understanding how the protein sirtuin 6 (SIRT6) influences the growth and spread of melanoma, a serious skin cancer. Researchers are examining the mechanisms by which SIRT6 contributes to melanoma's resistance to existing treatments and its role in promoting cancer cell proliferation. By using both laboratory and animal models, the study aims to identify new therapeutic strategies that target SIRT6 to improve melanoma management. The findings could lead to the development of innovative treatments that are more effective against this aggressive cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with malignant melanoma, particularly those who have experienced treatment resistance.
Not a fit: Patients with non-melanoma skin cancers or those without a diagnosis of melanoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for melanoma patients, potentially overcoming drug resistance and improving survival rates.
How similar studies have performed: Previous research has shown promising results in targeting sirtuins for cancer treatment, indicating that this approach may be effective.
Where this research is happening
Madison, United States
- Wm S. Middleton Memorial Veterans Hosp — Madison, United States (Active)
Researchers
- Principal investigator: Ahmad, Nihal — Wm S. Middleton Memorial Veterans Hosp
- Study coordinator: Ahmad, Nihal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.