Investigating the role of a protein in liver cancer development
Role of STEAP2 protein in hepatocarcinogenesis
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · NIH-10880253
This study is looking at how certain proteins, like STEAP2, might affect the growth of liver cancer in patients, with the hope of finding new ways to treat the disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-10880253 on ClinicalTrials.gov |
What this research studies
This research aims to uncover the molecular mechanisms that contribute to the rising rates of hepatocellular carcinoma (HCC) in the United States. By analyzing RNA samples from both tumor and adjacent non-tumor liver tissues of local HCC patients, the study focuses on the STEAP2 protein, which is involved in the transport of essential metals like iron and copper. The researchers are examining how changes in the expression of STEAP2 and related genes may influence tumor growth and progression. This work could lead to a better understanding of HCC and potential new therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with hepatocellular carcinoma or those at high risk for developing liver cancer.
Not a fit: Patients with liver cancer not related to the mechanisms being studied or those with other types of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating liver cancer.
How similar studies have performed: Other research has shown promising results in understanding cancer mechanisms through similar molecular approaches, indicating potential for success in this area.
Where this research is happening
SAN ANTONIO, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCIENCE CENTER — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SUN, LUZHE — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- Study coordinator: SUN, LUZHE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.