Investigating the role of a metal transporter in lung and immune health
ZIP8: A Metal Transporter with Pathophysiologic Roles in the Lung, Spleen, and Placenta
This study is looking at a protein called ZIP8 that helps move important metals into cells, especially in the lungs, and aims to learn how it works during infections and other health issues, which could help improve treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10907674 on NIH RePORTER |
What this research studies
This research focuses on ZIP8, a protein that transports essential metals into cells, particularly in the lungs, spleen, and placenta. By using specially designed mouse models, the study aims to understand how ZIP8 functions during normal conditions and diseases, especially in response to lung infections. The researchers will explore how ZIP8 affects immune responses and nutrient transport, which could lead to new insights into treating related health issues. Patients may benefit from a better understanding of how metal transport impacts their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with lung infections or conditions related to metal transport abnormalities.
Not a fit: Patients with conditions unrelated to lung health or metal transport may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for lung infections and related diseases by targeting metal transport mechanisms.
How similar studies have performed: Previous research has shown promising results in understanding the role of metal transporters in various diseases, suggesting potential for success in this area.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Kim, Airie — University of California Los Angeles
- Study coordinator: Kim, Airie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.