NIH-funded research R01 grant

Investigating the role of 11-oxyandrogens in aging and health.

Official title: 11-Oxyandrogens and Aging: Health Implications

Funded at University of Michigan at Ann Arbor · NIH-10992675 · Data updated 2026-11-12

This study is looking at how certain hormones called 11-oxyandrogens change in the body as we get older, and it’s for both men and women who want to understand how these changes might affect their health, especially regarding prostate cancer and bone health.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startFebruary 15, 2023
Project endNovember 30, 2027
Funding year2025
Award (this year)$508,039
NIH project number5R01AG080516-03
Project IDNIH-10992675 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older, particularly those experiencing age-related health changes.

Less likely to help

Patients who are not adults or those with conditions unrelated to androgen levels may not benefit from this research.

What this research studies

This research explores how specific adrenal androgens, known as 11-oxyandrogens, behave in the body as people age. It aims to understand the levels of these androgens in both men and women and their potential effects on health, particularly in relation to conditions like prostate cancer and bone health. By analyzing blood samples from participants, the study will track changes in these hormone levels and their associations with various health markers. This could provide insights into how aging affects hormone production and overall health.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of age-related health issues linked to hormone levels.

How similar studies have gone: Previous research has shown promising results in understanding hormone levels and their health implications, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Turcu, Adina F — University of Michigan at Ann Arbor
  • Study coordinator: Turcu, Adina F

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.