Investigating the relationship between jaw structure and jaw joint disorders

ATTRACT: Assessment of Temporomandibular JoinT MoRphology, Mechanics, And Mechanobiology in Class II and III Target and Surgical Phenotypes

NIH-funded research Clemson University · NIH-11005734

This study is looking at how certain jaw shapes can affect the jaw joint and cause problems, especially for people with specific jaw deformities, so they can learn more about their condition and possible treatments.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionClemson University NIH-funded
Lab location1 site (Clemson, United States)
Project IDNIH-11005734 on NIH RePORTER

What this research studies

This research focuses on understanding how specific jaw deformities, such as Class II and Class III skeletal deformities, relate to disorders of the temporomandibular joint (TMJ). By examining the morphology, mechanics, and biological responses of the jaw joint, the study aims to uncover the underlying causes of TMJ dysfunction, particularly in individuals with craniofacial abnormalities. The research employs advanced imaging and biomechanical analysis techniques to assess the impact of jaw structure on joint function and health. Patients with these deformities may gain insights into their condition and potential treatment options.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older with Class II or Class III skeletal deformities.

Not a fit: Patients without craniofacial skeletal deformities or those with Class I skeletal structure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for patients suffering from TMJ disorders associated with jaw deformities.

How similar studies have performed: Previous research has shown promising results in understanding the biomechanics of TMJ disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

Clemson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.