Investigating the properties of liquid organelles in cells
Structure-function properties in liquid organelles
This study is exploring special liquid-like structures in our cells that help them work properly, and the researchers want to find new ways to understand how these structures are organized, which could help us learn more about how our cells function and how they might be linked to diseases like cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kansas State University NIH-funded |
| Lab location | 1 site (Manhattan, United States) |
| Project ID | NIH-10829434 on NIH RePORTER |
What this research studies
This research focuses on understanding biomolecular condensates, which are liquid-like structures within cells that play crucial roles in various cellular functions. The team will develop new methods to identify and characterize the structure of these condensates, which are typically disordered and challenging to study using traditional techniques. By using theoretical modeling and iterative refinement, the researchers aim to uncover the hidden organization within these liquid systems that contributes to their functionality. This work could provide insights into how cellular processes are regulated and how they may relate to diseases like cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with cancers or other conditions related to cellular dysfunction.
Not a fit: Patients with conditions unrelated to cellular processes or those not involving biomolecular condensates may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for targeting cellular processes involved in diseases such as cancer.
How similar studies have performed: While the study of biomolecular condensates is a growing field, the specific methods proposed here are innovative and not widely tested.
Where this research is happening
Manhattan, United States
- Kansas State University — Manhattan, United States (Active)
Researchers
- Principal investigator: Schmit, Jeremy David — Kansas State University
- Study coordinator: Schmit, Jeremy David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.