Investigating the progression of liver cirrhosis and its outcomes.
Liver Cirrhosis Network: Clinical Research Centers
This study is looking at how liver cirrhosis gets worse over time in people with conditions like nonalcoholic fatty liver disease, alcohol-related liver issues, and those living with HIV, so we can find better ways to keep track of and manage their liver health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10909124 on NIH RePORTER |
What this research studies
This research focuses on understanding how liver cirrhosis progresses, particularly in patients with nonalcoholic steatohepatitis (NASH), alcohol-induced liver disease (ALD), and those living with HIV. It involves a multicenter, observational approach where patients with compensated cirrhosis will be enrolled and followed over time. The study aims to collect data and biological samples to evaluate various factors that contribute to the progression of cirrhosis and its associated clinical events. By identifying these factors, the research seeks to develop better tools for monitoring and managing liver disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with compensated cirrhosis, particularly those with NASH, ALD, or HIV.
Not a fit: Patients with liver cirrhosis who are not compensated or those with other unrelated liver conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for patients with liver cirrhosis.
How similar studies have performed: Other research has shown promise in understanding liver disease progression using similar observational approaches, indicating potential for success in this study.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Sanyal, Arun J — Virginia Commonwealth University
- Study coordinator: Sanyal, Arun J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.