Investigating the progression of dementia with Lewy bodies
Single-nuclei multiomic analysis of DLB progression
This study is looking into dementia with Lewy bodies to better understand how it affects the brain, and it's for anyone interested in learning more about this condition and how it develops over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-10503442 on NIH RePORTER |
What this research studies
This research focuses on understanding dementia with Lewy bodies (DLB), a type of neurodegenerative dementia that has not been thoroughly studied compared to other conditions like Parkinson's disease. The team will analyze various cell types in the brain to uncover how they contribute to the disease's progression. Using advanced techniques, they will examine postmortem brain tissues to track changes in gene expression and chromatin accessibility over time. This comprehensive approach aims to provide insights into the cellular mechanisms underlying DLB.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with dementia with Lewy bodies or those showing symptoms of this condition.
Not a fit: Patients with other forms of dementia, such as Alzheimer's disease without Lewy body involvement, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new treatments for dementia with Lewy bodies.
How similar studies have performed: While research on DLB is limited, similar approaches in studying other neurodegenerative diseases have shown promising results.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Kim, Yoon-Seong — Rutgers Biomedical and Health Sciences
- Study coordinator: Kim, Yoon-Seong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.