Investigating the pathology of frontotemporal lobar degeneration (FTLD)

Neuropathology Core

NIH-funded research Mayo Clinic Rochester · NIH-10889907

This study is all about learning more about frontotemporal lobar degeneration (FTLD) to help improve research and treatment, and it’s for anyone affected by this condition, as it brings together experts to look at brain tissue and other important information to better understand how FTLD works.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10889907 on NIH RePORTER

What this research studies

This research focuses on understanding the complex pathology of frontotemporal lobar degeneration (FTLD), a type of neurodegenerative disease. It aims to enhance research collaboration within the ALLFTD consortium by promoting tissue-based studies and facilitating standardized data collection across multiple sites. The team of leading experts will conduct neuropathological assessments and collect both fixed and frozen tissue samples for further investigation. By linking clinical, genetic, imaging, and biomarker data to neuropathological findings, this research seeks to deepen our understanding of FTLD and its various subtypes.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with frontotemporal lobar degeneration or related neurodegenerative conditions.

Not a fit: Patients with other types of dementia or neurodegenerative diseases that are not related to FTLD may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic and treatment strategies for patients with frontotemporal lobar degeneration.

How similar studies have performed: Previous research has shown success in understanding neurodegenerative diseases through tissue-based studies, making this approach promising.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.