Investigating the pain-relieving effects of minor cannabinoids and terpenes from cannabis

Analgesic efficacy of single and combined minor cannabinoids and terpenes

NIH-funded research Temple Univ of the Commonwealth · NIH-10661039

This study is looking at how different parts of the cannabis plant can help reduce pain, especially for people dealing with chemotherapy or dental problems, and how they work alongside common pain medications like morphine.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTemple Univ of the Commonwealth NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10661039 on NIH RePORTER

What this research studies

This research aims to explore how specific components of the cannabis plant, particularly minor cannabinoids and terpenes, work together to alleviate pain. The study will use rodent models to assess the effectiveness of these compounds in preventing pain related to chemotherapy and dental issues. Additionally, it will evaluate how these cannabis components interact with traditional pain medications like morphine. By understanding these interactions, the research seeks to identify new pain management strategies that could be beneficial for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic pain, particularly those related to chemotherapy or dental procedures.

Not a fit: Patients who do not experience pain or those with conditions unrelated to the types of pain being studied may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer pain management options for patients suffering from various types of pain.

How similar studies have performed: While there is growing interest in the analgesic properties of cannabis, this specific combination of minor cannabinoids and terpenes is relatively novel and has not been extensively tested in clinical settings.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.