Investigating the occurrence and effects of Pediatric Acute-Onset Neuropsychiatric Syndrome in children
Official title: Feasibility of a study to determine the incidence, spectrum, course and outcome of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) in a diverse group of children
Funded at University of Wisconsin-Madison · NIH-11036615 · Data updated 2026-11-12
This study is looking at how many kids in different communities across the U.S. have Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and PANDAS, and it will help us understand the symptoms they experience, like obsessive-compulsive disorder, to better support their health and behavior.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $246,884 |
| NIH project number | 1R21MH138881-01 |
| Project ID | NIH-11036615 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-17 who exhibit symptoms of PANS or PANDAS.
✕Less likely to help
Patients who do not have symptoms of PANS or PANDAS may not benefit from this research.
What this research studies
This research aims to explore how common Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and its related condition, PANDAS, are among children in diverse communities across the United States. The study will involve identifying and enrolling children who exhibit symptoms such as obsessive-compulsive disorder and other neuropsychiatric issues, with a focus on understanding the range of symptoms and their progression. By collecting data from various populations, the research seeks to create a clearer picture of these conditions and their impacts on children's health and behavior.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of PANS and PANDAS, ultimately improving treatment options for affected children.
How similar studies have gone: While there have been studies on PANS and PANDAS, this research aims to provide a novel perspective by focusing on a broader and more diverse population.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Wald, Ellen — University of Wisconsin-Madison
- Study coordinator: Wald, Ellen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.