Investigating the neurological effects of SARS-CoV-2 in people with HIV-1.
Longitudinal determination of nervous system consequences of SARS-CoV-2 in virologically suppressed people with HIV-1 treated in early infection
This study is looking at how COVID-19 affects the brain and mental health of people living with HIV, and it’s for those who want to understand the combined impact of both viruses on their well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10613789 on NIH RePORTER |
What this research studies
This research focuses on understanding how SARS-CoV-2, the virus that causes COVID-19, affects the nervous system in individuals who are living with HIV-1. By analyzing data from a unique cohort of patients who received early treatment for HIV, the study aims to explore the combined impact of both viruses on cognitive function and mental health. Participants will undergo various assessments, including brain imaging and cognitive evaluations, to track changes over time. The research seeks to uncover potential risks and complications that may arise from co-infection with these viruses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV-1 who have been treated early with antiretroviral therapy and may also be at risk of contracting SARS-CoV-2.
Not a fit: Patients who are not living with HIV-1 or those who have not received early treatment for HIV-1 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of neurological complications in patients with HIV-1 who contract SARS-CoV-2.
How similar studies have performed: Previous research has indicated potential neurological complications associated with COVID-19, but this study aims to provide novel insights specifically related to co-infection with HIV-1.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Spudich, Serena S — Yale University
- Study coordinator: Spudich, Serena S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.