Investigating the neurological effects of sarcoidosis and its immune responses
Neurosarcoidosis: Clinical Phenotype, Biomarkers and Immunopathogensis
This study is looking at how neurosarcoidosis affects the nervous system in people with sarcoidosis, aiming to understand the different symptoms and immune factors involved, so we can better recognize and treat this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10906927 on NIH RePORTER |
What this research studies
This research focuses on understanding neurosarcoidosis, a condition that affects the nervous system in patients with sarcoidosis. It aims to identify the different clinical manifestations of the disease, such as meningitis and encephalitis, and to analyze the immune profiles and genetic factors associated with these conditions. By collecting cerebrospinal fluid and clinical data from patients, the study seeks to uncover the underlying immune mechanisms and potential infectious agents that may trigger neurosarcoidosis. This comprehensive approach will help in defining the disease's clinical phenotypes and their relationship with immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with sarcoidosis who are experiencing neurological symptoms.
Not a fit: Patients without a diagnosis of sarcoidosis or those who do not exhibit neurological manifestations of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for patients suffering from neurosarcoidosis.
How similar studies have performed: Previous research has shown promising results in understanding the immune responses in sarcoidosis, making this approach both relevant and potentially impactful.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Pardo-Villamizar, Carlos a — Johns Hopkins University
- Study coordinator: Pardo-Villamizar, Carlos a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.