Investigating the mTOR pathway's role in fatigue during cancer treatment
Multi-omic Evaluation of the mTOR pathway in Radiotherapy-Related Fatigue
This study is looking at why men with prostate cancer feel tired during radiation therapy, hoping to find out how certain biological changes might be causing this fatigue, so we can help make them feel better while they’re being treated.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10665092 on NIH RePORTER |
What this research studies
This research focuses on understanding cancer-related fatigue, particularly in prostate cancer patients undergoing radiation therapy. It aims to explore how changes in the mTOR signaling pathway may contribute to fatigue by examining the interactions among various biomolecules involved. The study will utilize advanced techniques in genomics and bioinformatics to analyze gene expression and identify potential mechanisms behind fatigue. By uncovering these connections, the research seeks to improve symptom management for patients experiencing fatigue during treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are prostate cancer patients who are currently receiving radiation therapy and experiencing fatigue.
Not a fit: Patients who are not undergoing radiation therapy or those with fatigue unrelated to cancer treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies for cancer-related fatigue, enhancing the quality of life for patients undergoing treatment.
How similar studies have performed: Previous research has shown promising results in understanding the biological mechanisms of cancer-related fatigue, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Gonzalez-Mercado, Velda Janet — New York University
- Study coordinator: Gonzalez-Mercado, Velda Janet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.