Investigating the molecular causes of aging and Alzheimer's disease using advanced imaging techniques
Elucidating Molecular Drivers of Aging and Alzheimer's Disease via Multimodal Imaging Mass Spectrometry
['FUNDING_R01'] · VANDERBILT UNIVERSITY · NIH-10881896
This study is looking at how aging and Alzheimer's disease affect the brain by using special imaging techniques to create detailed maps of brain tissues, which could help us understand the disease better and find new treatments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY (nih funded) |
| Locations | 1 site (Nashville, UNITED STATES) |
| Trial ID | NIH-10881896 on ClinicalTrials.gov |
What this research studies
This research aims to explore the molecular complexities of aging and Alzheimer's disease by utilizing advanced imaging technologies to analyze brain tissues. By creating detailed molecular atlases, the study seeks to identify key molecules and pathways that contribute to the disease's heterogeneity. The research will involve collaboration with leading centers and utilize sophisticated biocomputational tools to document specific molecular changes in brain cells associated with normal aging and Alzheimer's. This comprehensive approach could lead to a better understanding of the disease and inform the development of targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those experiencing normal aging.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise treatments for Alzheimer's disease and improve patient outcomes.
How similar studies have performed: Previous research has shown promise in using multimodal imaging techniques to understand complex diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, UNITED STATES
- VANDERBILT UNIVERSITY — Nashville, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SPRAGGINS, JEFFREY M — VANDERBILT UNIVERSITY
- Study coordinator: SPRAGGINS, JEFFREY M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease brain