Investigating the MIND diet's effects on cognitive impairment in breast cancer survivors
Official title: The MIND-BC Study: MIND diet for Breast cancer Cognition
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11098885 · Data updated 2026-11-12
This study is looking at whether following the MIND diet can help improve memory and focus for breast cancer survivors who are having trouble with thinking clearly after treatment, making it a friendly and practical way to boost their brain health and overall well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $713,235 |
| NIH project number | 1R01CA299480-01 |
| Project ID | NIH-11098885 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer survivors who are experiencing cognitive impairment following their treatment.
✕Less likely to help
Patients who are not breast cancer survivors or those without cognitive impairment may not benefit from this research.
What this research studies
This research focuses on how the MIND diet, which combines elements of the Mediterranean and DASH diets, may help improve cognitive function in breast cancer survivors experiencing cancer-related cognitive impairment (CRCI). The study will evaluate the impact of this dietary intervention on cognitive outcomes such as memory and attention, as well as its potential to reduce inflammation and oxidative stress. Participants will be monitored over several years to assess changes in cognitive abilities and overall quality of life. The approach is designed to be accessible and practical for survivors, aiming to provide a sustainable dietary option that could enhance their cognitive health.
Why it matters
Potential benefit: If successful, this research could lead to effective dietary strategies that improve cognitive function and quality of life for breast cancer survivors.
How similar studies have gone: Previous research has shown that the MIND diet can improve cognitive outcomes in various populations, suggesting a promising avenue for addressing CRCI in breast cancer survivors.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Crowder, Sylvia — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Crowder, Sylvia
Related research
Other NIH-funded projects on the same topics.
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MIND diet to support thinking and memory after breast cancer
This project looks at whether following the MIND diet helps thinking and memory in breast cancer survivors who have treatment-related cognitive changes.
-
How breast cancer hormone therapy may affect memory and thinking over time
This project looks at whether aromatase inhibitor hormone treatments for postmenopausal breast cancer are linked with changes in thinking and memory in women, compared to women with breast cancer who did not take these drugs and to women without cancer.
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Investigating the cognitive effects of breast cancer treatment over time
This study is looking at how certain breast cancer treatments, especially anti-estrogen medications, might impact thinking and memory in survivors over five years, comparing their experiences to other women with and without breast cancer.
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Aimed at helping doctors in Nigeria follow international guideline-based breast cancer care to improve outcomes for women with breast cancer.
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This study looks at how inherited genes and gene activity affect triple-negative breast cancer in people of African ancestry to better understand why outcomes can be worse.
-
Translational breast cancer research to improve treatment options
A comprehensive program at Baylor College of Medicine is focusing on breast cancer; researchers will advance targeted therapies and biomarkers to help patients with aggressive or hard-to-treat forms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.