Investigating the lung effects of menthol and tobacco flavored e-cigarettes

Pulmonary toxicological evaluation and chemical interactions of menthol, mint, and tobacco flavored e-cigarette products

NIH-funded research Purdue University · NIH-10930941

This study is looking at how menthol, mint, and tobacco-flavored e-cigarettes can harm lung health, especially with long-term use, to help people understand the risks of flavored vaping products.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPurdue University NIH-funded
Lab location1 site (West Lafayette, United States)
Project IDNIH-10930941 on NIH RePORTER

What this research studies

This research examines the toxic effects of menthol, mint, and tobacco flavored e-cigarettes on lung health. It utilizes cell culture and mouse models to identify harmful chemicals in these products and their biological impacts. The study aims to understand how these flavors may interact chemically and contribute to lung toxicity, particularly with prolonged exposure. By validating the toxicants found in e-cigarette aerosols, the research seeks to provide insights into the health risks associated with flavored vaping products.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who regularly use menthol or tobacco flavored e-cigarettes and may be experiencing respiratory issues.

Not a fit: Patients who do not use e-cigarettes or are not affected by respiratory conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and regulation of flavored e-cigarettes, potentially reducing lung-related health issues for users.

How similar studies have performed: Previous research has indicated potential health risks associated with flavored e-cigarettes, suggesting that this investigation builds on established findings rather than exploring entirely novel territory.

Where this research is happening

West Lafayette, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Lung InjuryAcute Pulmonary Injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.