Investigating the long-term effects of radiation exposure in nonhuman primates
The Wake Forest Nonhuman Primate Radiation Survivor Cohort
['FUNDING_U01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-10891607
This study is looking at how radiation exposure affects health over time, especially in normal tissues, by observing a special group of monkeys that have survived it, to help improve treatments for people who have been exposed to radiation.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-10891607 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the delayed effects of radiation exposure on health, particularly how it impacts normal tissues over time. By studying a unique group of nonhuman primates that have survived radiation exposure, researchers aim to identify cellular and metabolic changes that lead to serious health issues like organ dysfunction and diabetes. The study involves comprehensive clinical examinations, imaging techniques, and pathology assessments over many years to gather critical data on the long-term consequences of radiation. This information could help improve medical responses and treatments for individuals affected by radiation exposure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced significant radiation exposure and are at risk for long-term health effects.
Not a fit: Patients who have not been exposed to radiation or who are not experiencing any adverse health effects from such exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment of radiation-related health issues, potentially improving outcomes for affected patients.
How similar studies have performed: Previous research has shown success in understanding radiation effects through animal models, making this approach both relevant and promising.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CLINE, J. MARK — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: CLINE, J. MARK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus