Investigating the long-term effects of preeclampsia on offspring through B cells
B Cells in Preeclampsia: Long-term Effects on Offspring
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF MISSISSIPPI MED CTR · NIH-11162701
This study is looking at how preeclampsia during pregnancy can impact the immune system and long-term health of both mothers and their children, and it’s testing a new treatment that might help prevent some of these health issues.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MISSISSIPPI MED CTR (nih funded) |
| Locations | 1 site (JACKSON, UNITED STATES) |
| Trial ID | NIH-11162701 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how preeclampsia, a pregnancy complication characterized by high blood pressure and organ dysfunction, affects the immune system and long-term health of offspring. The study examines the role of activated B cells and their production of specific autoantibodies that may contribute to health issues in both mothers and their children. By exploring a novel peptide treatment that has shown promise in preclinical models, the research aims to identify potential preventive strategies for the adverse effects associated with preeclampsia. Patients may be involved in the study to help assess the implications of these findings on future health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation include pregnant women diagnosed with preeclampsia and their offspring, particularly those at risk for long-term health complications.
Not a fit: Patients who have not experienced preeclampsia or do not have a family history of related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for health issues in children born to mothers who experienced preeclampsia.
How similar studies have performed: Previous research has shown promising results in understanding the immune mechanisms involved in preeclampsia, but this specific approach using the novel peptide is relatively novel.
Where this research is happening
JACKSON, UNITED STATES
- UNIVERSITY OF MISSISSIPPI MED CTR — JACKSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CAMPBELL, NATHAN E. — UNIVERSITY OF MISSISSIPPI MED CTR
- Study coordinator: CAMPBELL, NATHAN E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.