Investigating the long-term effects of electronic cigarette smoke on lung health
Translational Studies on Electronic Cigarette-derived Oxidants and their Long-term Pulmonary Effects
This study is looking at how the harmful chemicals in e-cigarette smoke might affect lung health over time, especially for people with chronic lung diseases like COPD, by testing these effects in mice.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project ID | NIH-10456627 on NIH RePORTER |
What this research studies
This research examines how exposure to oxidants from electronic cigarette aerosols affects lung health over time. By using advanced analytical techniques, the study measures the levels of harmful substances like free radicals and aldehydes in electronic cigarette products. The researchers aim to understand the potential negative impacts of these substances on chronic lung diseases, particularly chronic obstructive pulmonary disease (COPD). They will conduct long-term studies in mice to explore the relationship between electronic cigarette use and lung health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who currently use electronic cigarettes or have a history of tobacco use and are concerned about their lung health.
Not a fit: Patients who do not use electronic cigarettes or combustible tobacco products may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of lung health for individuals using electronic cigarettes.
How similar studies have performed: Previous research has indicated potential health risks associated with electronic cigarette use, suggesting that this study builds on existing knowledge rather than exploring an entirely novel area.
Where this research is happening
Hershey, United States
- Pennsylvania State Univ Hershey Med Ctr — Hershey, United States (Active)
Researchers
- Principal investigator: Sinha, Raghu — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Sinha, Raghu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.