Investigating the long-term effects of DHA supplements in toddlers born preterm

Long-term Effects and Safety of DHA Supplementation in Toddlerhood for Children born Preterm

NIH-funded research Research Inst Nationwide Children's Hosp · NIH-10875660

This study is looking at how giving DHA, a type of healthy fat, to toddlers who were born early might help their thinking and language skills as they grow, and it’s for families with preterm children who want to know if this supplement can make a difference in their child's development.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Inst Nationwide Children's Hosp NIH-funded
Lab location1 site (Columbus, United States)
Project IDNIH-10875660 on NIH RePORTER

What this research studies

This research examines how DHA (docosahexaenoic acid) supplementation during toddlerhood affects cognitive development in children born preterm. It aims to determine whether children who received DHA at age 1 show differences in cognitive abilities, language skills, and executive function compared to those who received a placebo. The study continues to follow participants from a previous trial to assess these long-term outcomes and explore genetic factors that may influence the effects of DHA. By understanding these impacts, the research seeks to ensure that interventions for preterm children are both safe and effective.

Who could benefit from this research

Good fit: Ideal candidates for this research are children who were born preterm and received DHA supplementation during their toddler years.

Not a fit: Patients who were not born preterm or did not receive DHA supplementation are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide insights into safe dietary interventions that enhance cognitive development in children born preterm.

How similar studies have performed: Previous research has indicated potential adverse effects of DHA supplementation, making this investigation both relevant and necessary.

Where this research is happening

Columbus, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.