Investigating the long-term effects of COVID-19 on individuals with Alzheimer's disease and related dementias.
Post-Acute Sequelae of SARS-CoV-2 Infection and Subsequent Disease Progression in Individuals with AD/ADRD: Influence of the Social and Environmental Determinants of Health
This study is looking at how COVID-19 might affect people with Alzheimer's and similar memory issues, to see if getting the virus makes their thinking and memory problems worse, while also considering how their surroundings and social situations play a role.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10751275 on NIH RePORTER |
What this research studies
This research focuses on understanding how COVID-19 affects individuals with cognitive impairments, particularly those with Alzheimer's disease and related dementias. It aims to explore the post-acute sequelae of SARS-CoV-2 infection, which may lead to worsening cognitive and memory disorders. By utilizing electronic health records, the study will analyze longitudinal data to identify the impact of COVID-19 on disease progression in these vulnerable populations. The research will also consider social and environmental factors that may influence health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias who have also had a COVID-19 infection.
Not a fit: Patients who have not been diagnosed with cognitive impairments or have not contracted COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive decline in patients recovering from COVID-19.
How similar studies have performed: Previous research has indicated that COVID-19 can lead to neurological complications, but this specific focus on cognitively impaired individuals is relatively novel.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Hu, Hui — Brigham and Women's Hospital
- Study coordinator: Hu, Hui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.