Investigating the long-term effects of COVID-19 on blood vessel health in people with obesity

Long-Term Endothelial Effects of COVID-19 in Obesity

NIH-funded research Beth Israel Deaconess Medical Center · NIH-11045704

This study is looking at how COVID-19 might affect blood vessel health over time, especially in people with obesity, and it’s for anyone who has had COVID-19 or is curious about its long-term effects on heart health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBeth Israel Deaconess Medical Center NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11045704 on NIH RePORTER

What this research studies

This research explores how COVID-19 affects the health of blood vessels over time, particularly in individuals with obesity. It aims to understand the long-lasting impacts of the virus on endothelial function, which is crucial for cardiovascular health. The study will involve comparing 100 individuals who have had COVID-19, both obese and non-obese, with 50 similar individuals who have not been infected. Researchers will analyze various factors, including inflammation and molecular pathways, to uncover the mechanisms behind any observed vascular dysfunction.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have a history of COVID-19 infection and are either obese or non-obese.

Not a fit: Patients who have not been infected with COVID-19 or those without obesity-related health issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular risks in patients who have recovered from COVID-19, especially those with obesity.

How similar studies have performed: Other research has indicated potential long-term cardiovascular effects following COVID-19 infection, suggesting that this investigation builds on existing findings.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions after COVID-19 infectionafter infection by SARS-CoV-2after SARS-CoV-2 infectionafter SARS-CoV2 infectionafter severe acute respiratory distress syndrome CoV-2 infection
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.