Investigating the links between hearing loss, cognitive decline, and dementia risk as we age
Shared Genetic and Environmental Influences on Age-Related Hearing Loss, Cognitive Decline, and Dementia Risk
This study is looking at how hearing loss and memory problems are connected as we get older, especially in Mexican American adults, to find out what genes and environmental factors might play a role, so we can better understand how to help prevent these issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11079480 on NIH RePORTER |
What this research studies
This research explores how age-related hearing loss and cognitive decline are interconnected and influenced by both genetic and environmental factors. By studying a diverse group of Mexican American participants, the research aims to identify specific genetic and environmental pathways that contribute to these conditions. Participants will undergo assessments of their hearing abilities, cognitive skills, and biomarkers associated with dementia. The findings could lead to a better understanding of how to prevent or mitigate these age-related issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are Mexican American individuals aged 18 and older who are experiencing age-related hearing loss or cognitive decline.
Not a fit: Patients who are younger than 18 years or do not have any signs of hearing loss or cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline and dementia in older adults.
How similar studies have performed: Previous studies have shown promising results in understanding the genetic correlations between hearing and cognitive abilities, supporting the potential success of this approach.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Mathias, Samuel Robert — Boston Children's Hospital
- Study coordinator: Mathias, Samuel Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.