Investigating the link between World Trade Center exposure and thyroid cancer in survivors

The Effect of WTC Exposure on Thyroid Cancer in the Survivor Population

['FUNDING_U01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10903700

This study is looking at whether breathing in dust from the World Trade Center affects the risk of thyroid cancer in kids and teens who were exposed, and it aims to understand how this exposure might lead to more serious cases of the disease.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10903700 on ClinicalTrials.gov

What this research studies

This research examines the potential connection between exposure to World Trade Center (WTC) dust and the development of thyroid cancer in individuals who were exposed, particularly focusing on children and adolescents. The study aims to analyze clinical, mutational, and pathological characteristics of thyroid cancer in WTC survivors compared to those who were not exposed. By assessing the impact of endocrine disruptors found in WTC dust, the research seeks to understand how early life exposure may lead to more aggressive forms of thyroid cancer. This comprehensive approach will provide valuable insights into the long-term health effects of WTC exposure.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who were under 18 years old at the time of the WTC exposure and have been diagnosed with thyroid cancer.

Not a fit: Patients who were not exposed to WTC dust or those who do not have a history of thyroid cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of thyroid cancer in WTC survivors, potentially informing treatment strategies.

How similar studies have performed: Previous research has indicated a concerning link between environmental exposures and cancer risk, suggesting that this investigation could yield significant findings.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.