Investigating the link between vitamin D, gut health, and dementia risk in older adults with chronic HIV.
Vitamin D and Gut Microbiota and Dementia Risk in Older Adults with Chronic HIV infection and Demographically Matched Community Controls
This study is looking at how vitamin D and gut health might affect the risk of dementia in older adults with chronic HIV, to find ways to help prevent Alzheimer's and similar conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-11136979 on NIH RePORTER |
What this research studies
This research explores how vitamin D levels and gut microbiota may influence the risk of developing dementia in older adults, particularly those over 65 years old living with chronic HIV infection. The study aims to identify potential modifiable risk factors for Alzheimer's dementia and related disorders by examining the relationship between gut health and vitamin D deficiency. Participants will be monitored for changes in their gut microbiome and vitamin D levels, and how these factors correlate with cognitive health over time. The findings could lead to new strategies for preventing dementia in vulnerable populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are living with chronic HIV infection.
Not a fit: Patients who are younger than 65 or do not have chronic HIV infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into preventing or delaying the onset of dementia in older adults with chronic HIV infection.
How similar studies have performed: Previous research has indicated potential links between gut health, vitamin D levels, and cognitive decline, suggesting that this approach may yield valuable insights.
Where this research is happening
East Lansing, United States
- Henry Ford Health + Michigan State University Health Sciences — East Lansing, United States (Active)
Researchers
- Principal investigator: Ezeamama, Amara E — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Ezeamama, Amara E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.