Investigating the link between uranium exposure and infertility in a community cohort.

Uranium Exposure and Infertility in Reproductive Partners in the Fernald Community Cohort

NIH-funded research University of Cincinnati · NIH-10666344

This study is looking at how being around uranium might affect the ability to have children for people who lived in the Fernald area, and it’s for anyone from that community who wants to help us understand the possible impacts on reproductive health.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Cincinnati NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10666344 on NIH RePORTER

What this research studies

This research examines how exposure to uranium may affect infertility in both men and women within the Fernald Community Cohort, a group of approximately 9,000 individuals who lived in an area with known uranium exposure from 1951 to 1989. The study utilizes historical data and biological samples collected over the years to explore the relationship between uranium exposure and reproductive health. By analyzing hormone levels and infertility rates, the research aims to uncover potential risks associated with environmental contaminants. Participants will be asked to provide information through questionnaires and may contribute biological samples for further analysis.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals from the Fernald Community Cohort who have experienced infertility issues.

Not a fit: Patients who have not been exposed to uranium or are not part of the Fernald Community Cohort may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of environmental factors contributing to infertility, potentially guiding public health interventions.

How similar studies have performed: Previous research has indicated potential links between environmental exposures and infertility, suggesting that this investigation could build on established findings.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.