NIH-funded research R21 grant

Investigating the link between uranium exposure and infertility in a community cohort.

Official title: Uranium Exposure and Infertility in Reproductive Partners in the Fernald Community Cohort

Funded at University of Cincinnati · NIH-10666344 · Data updated 2026-11-12

This study is looking at how being around uranium might affect the ability to have children for people who lived in the Fernald area, and it’s for anyone from that community who wants to help us understand the possible impacts on reproductive health.

More Infertility research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Cincinnati
NIH-funded
Lab location1 site (Cincinnati, United States)
Project startJuly 18, 2022
Project endJune 30, 2025
Funding year2023
Award (this year)$202,604
NIH project number5R21ES032112-02
Project IDNIH-10666344 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals from the Fernald Community Cohort who have experienced infertility issues.

Less likely to help

Patients who have not been exposed to uranium or are not part of the Fernald Community Cohort may not benefit from this research.

What this research studies

This research examines how exposure to uranium may affect infertility in both men and women within the Fernald Community Cohort, a group of approximately 9,000 individuals who lived in an area with known uranium exposure from 1951 to 1989. The study utilizes historical data and biological samples collected over the years to explore the relationship between uranium exposure and reproductive health. By analyzing hormone levels and infertility rates, the research aims to uncover potential risks associated with environmental contaminants. Participants will be asked to provide information through questionnaires and may contribute biological samples for further analysis.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of environmental factors contributing to infertility, potentially guiding public health interventions.

How similar studies have gone: Previous research has indicated potential links between environmental exposures and infertility, suggesting that this investigation could build on established findings.

Where this research is happening

  • University of Cincinnati
    Cincinnati, United States
    Active

Researchers

  • Principal investigator: Pinney, Susan Mengel — University of Cincinnati
  • Study coordinator: Pinney, Susan Mengel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.