Investigating the link between rheumatoid arthritis and lung disease
Rheumatoid Arthritis-Related Autoantibodies, Articular Inflammation, and RA-Associated Interstitial Lung Disease
This study is looking at how rheumatoid arthritis might cause lung problems and aims to find early signs of these issues in people with RA, so we can help prevent or better manage any lung complications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10868767 on NIH RePORTER |
What this research studies
This research focuses on understanding how rheumatoid arthritis (RA) can lead to interstitial lung disease (ILD), a serious complication. It examines the role of specific autoantibodies and inflammation in the joints that may predict the development of lung issues in RA patients. By analyzing blood samples and imaging data, the study aims to identify early indicators of lung disease in individuals with RA. This could help in developing targeted interventions to prevent or manage lung complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with rheumatoid arthritis, particularly those showing signs of joint inflammation.
Not a fit: Patients without a diagnosis of rheumatoid arthritis or those with other unrelated lung conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of lung disease in patients with rheumatoid arthritis.
How similar studies have performed: Previous research has indicated a connection between rheumatoid arthritis and lung disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Sparks, Jeffrey Andrew — Brigham and Women's Hospital
- Study coordinator: Sparks, Jeffrey Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.