Investigating the link between pesticide use and Valley fever cases

Exploratory study of pesticide use and coccidioidomycosis

NIH-funded research Stanford University · NIH-11118419

This study is looking at whether using certain pesticides, like fungicides and rodenticides, might change the amount of the Coccidioides fungus in the environment, which can cause Valley fever, and it’s especially interested in how climate change and farming practices might play a role in this.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-11118419 on NIH RePORTER

What this research studies

This research explores how the use of pesticides, particularly fungicides and rodenticides, may influence the risk of coccidioidomycosis, commonly known as Valley fever. It examines the relationship between pesticide application and the presence of the Coccidioides fungus in the environment, which can lead to increased cases of the disease. By analyzing various data sets, the study aims to determine if pesticides affect the density of this pathogen in soil and how this might correlate with human cases of the illness. The research is particularly focused on the impact of climate change on the geographic spread of the fungus and the role of agricultural practices in this dynamic.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living in areas with high rates of coccidioidomycosis, particularly those who may have been exposed to agricultural practices involving pesticide use.

Not a fit: Patients who do not live in endemic areas or who have not been exposed to the Coccidioides fungus are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of coccidioidomycosis, potentially reducing the incidence of this disease in affected populations.

How similar studies have performed: Previous research has indicated a potential link between environmental factors and the incidence of coccidioidomycosis, suggesting that this study could build on existing knowledge, although the specific focus on pesticides is relatively novel.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.