Investigating the link between obesity, insulin resistance, and asthma severity
Official title: Insulin Resistance, Pre-Diabetes, and Diabetes in Obesity-Associated Asthma
Funded at Baylor College of Medicine · NIH-11072964 · Data updated 2026-11-12
This study is looking at how insulin resistance, pre-diabetes, and diabetes impact asthma control in people with obesity who have asthma, especially those getting weight loss surgery, to help understand how these conditions might affect their breathing and overall health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | May 15, 2021 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $207,087 |
| NIH project number | 5K23HL151669-05 |
| Project ID | NIH-11072964 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are obese individuals diagnosed with asthma, particularly those experiencing frequent exacerbations.
✕Less likely to help
Patients who are not obese or do not have asthma may not benefit from this research.
What this research studies
This research explores how insulin resistance, pre-diabetes, and diabetes affect asthma control and severity in obese individuals. By analyzing data from electronic health records and conducting a cohort study of obese asthma patients undergoing bariatric surgery, the study aims to uncover the relationship between these metabolic disorders and asthma exacerbations. Patients will be monitored for changes in lung function and insulin resistance over time, providing valuable insights into their health.
Why it matters
Potential benefit: If successful, this research could lead to improved management strategies for asthma in obese patients, potentially reducing the frequency and severity of asthma attacks.
How similar studies have gone: Previous research has indicated a connection between obesity and asthma severity, suggesting that this approach may yield significant findings.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Wu, Tianshi David — Baylor College of Medicine
- Study coordinator: Wu, Tianshi David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.