Investigating the link between menopause, fat hormones, and heart health in older women
Adipokines, Sex Hormones and Cardiac Dysfunction in Postmenopausal Women of the MESA Study – An analysis of Secondary Data
This study is looking at how menopause affects heart health in women by exploring the role of certain hormones and using advanced imaging to see how these changes might impact the heart, with the goal of finding better ways to prevent and treat heart problems after menopause.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10690544 on NIH RePORTER |
What this research studies
This research examines how menopause affects heart health in women, particularly focusing on the role of fat hormones called adipokines. By analyzing data from the Multi-Ethnic Study of Atherosclerosis (MESA), the study aims to understand how these hormones influence heart structure and function, especially in postmenopausal women. The research utilizes advanced imaging techniques like MRI to assess cardiac health and explores the relationship between menopausal age, body composition, and heart failure risk. Patients may benefit from insights that could lead to better prevention and treatment strategies for heart issues related to menopause.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women, particularly those experiencing heart health issues or obesity.
Not a fit: Patients who are not postmenopausal or do not have concerns related to heart health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of heart health in postmenopausal women.
How similar studies have performed: Previous research has shown associations between menopause and heart health, but this study aims to explore these relationships in a novel way using comprehensive data analysis.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Ebong, Imo a — University of California at Davis
- Study coordinator: Ebong, Imo a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.