Investigating the link between inflammation, heart health, and Alzheimer's risk in rheumatoid arthritis patients
Temporal associations between systemic inflammation, cardiovascular risk profile and development of Alzheimer’s disease and related dementias in patients with rheumatoid arthritis
This study is looking at how inflammation and heart health might affect the risk of developing Alzheimer's and other types of dementia in people with rheumatoid arthritis, so we can find better ways to prevent these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11077325 on NIH RePORTER |
What this research studies
This research focuses on understanding how systemic inflammation and cardiovascular risk factors may influence the development of Alzheimer's disease and related dementias in patients with rheumatoid arthritis. By examining the long-term relationships between these factors, the study aims to identify potential pathways that could lead to improved prevention strategies. Patients with rheumatoid arthritis may be monitored for cardiovascular events and cognitive changes over time, providing valuable insights into their health. The research will also involve mentoring trainees in patient-oriented research to enhance the overall understanding of these complex interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with rheumatoid arthritis who may be at risk for Alzheimer's disease or related dementias.
Not a fit: Patients without rheumatoid arthritis or those who do not have concerns about Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for Alzheimer's disease in patients with rheumatoid arthritis.
How similar studies have performed: Previous research has shown promising results in understanding the connections between inflammation, cardiovascular health, and cognitive decline, making this approach both relevant and potentially impactful.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Myasoedova, Elena — Mayo Clinic Rochester
- Study coordinator: Myasoedova, Elena
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.