Investigating the link between HPV, HIV, and oral bacteria in young people in Nigeria
Official title: HPV, HIV and Oral Microbiota Interplay in Nigerian Youth (HOMINY)
Funded at University of Pennsylvania · NIH-11141440 · Data updated 2026-11-12
This study is looking at how oral HPV infections happen in kids and teens, especially those with HIV, to find ways to prevent related cancers, and it compares children born to mothers with HIV to those born to mothers without it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $956,631 |
| NIH project number | 7R01DE032216-03 |
| Project ID | NIH-11141440 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and adolescents, particularly those born to HIV-infected mothers or those living with HIV themselves.
✕Less likely to help
Patients who are not within the age range of children and adolescents or those who are not affected by HIV may not benefit from this research.
What this research studies
This research explores how oral HPV infections develop in children and adolescents, particularly those living with HIV. It aims to understand the natural history of these infections and the role of the oral microbiome in their persistence. By comparing children born to HIV-infected mothers with those born to uninfected mothers, the study seeks to identify key factors that could help prevent HPV-related cancers. The approach includes a prospective observational study to gather comprehensive data on these populations.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for HPV-related cancers in young people living with HIV.
How similar studies have gone: While there is ongoing research into HPV and HIV interactions, this specific focus on the oral microbiome in young populations is relatively novel and has not been extensively studied.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Coker, Modupe — University of Pennsylvania
- Study coordinator: Coker, Modupe
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.