Investigating the link between HIV and liver cancer in Africa
HIV and HCC in Africa: The H2A Consortium
This study is looking at how HIV and chronic infections like hepatitis B and C can lead to liver cancer in Africa, and it aims to find new treatments to help HIV-positive patients and improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11089983 on NIH RePORTER |
What this research studies
This research focuses on understanding how HIV and chronic infections like hepatitis B and C contribute to the development of hepatocellular carcinoma (HCC) in Africa. The project involves collaboration between institutions in East and West Africa and aims to develop strategies to reduce the burden of HCC among HIV-positive patients. By enhancing local research capacity and infrastructure, the team will explore medical treatments that could interrupt or reverse the effects of these infections on liver cancer. Patients may be involved in clinical activities and benefit from new treatment approaches being developed.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV in sub-Saharan Africa, particularly those at risk for or diagnosed with hepatocellular carcinoma.
Not a fit: Patients who do not have HIV or chronic hepatitis infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for liver cancer in patients with HIV in Africa.
How similar studies have performed: Previous research has shown that addressing chronic infections can significantly impact cancer outcomes, suggesting that this approach may be effective.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kirk, Gregory D — Johns Hopkins University
- Study coordinator: Kirk, Gregory D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.