Investigating the link between HIV and liver cancer in Africa
HIV and HCC in Africa: The H2A Consortium
This study is looking at how HIV and other infections like hepatitis B and C can lead to liver cancer in people in Africa, and it aims to find better ways to help those who are at risk and need treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10903765 on NIH RePORTER |
What this research studies
This research focuses on the relationship between HIV and hepatocellular carcinoma (HCC), a common and deadly cancer in Africa. It aims to understand how chronic infections like hepatitis B and C, along with HIV, contribute to the development of HCC in patients. The study involves collaboration between institutions in East and West Africa, aiming to build local research capacity and develop strategies to reduce the burden of HCC. By forming a large cohort of patients, the research will identify those who need treatment for hepatitis B and assess the effectiveness of interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are also co-infected with hepatitis B or C.
Not a fit: Patients without HIV or those who do not have chronic hepatitis infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with HIV and reduce the incidence of liver cancer in Africa.
How similar studies have performed: Previous research has shown that addressing chronic infections can significantly impact cancer outcomes, suggesting potential success for this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kirk, Gregory D — Johns Hopkins University
- Study coordinator: Kirk, Gregory D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.