Investigating the link between Helicobacter pylori infection, diet, and gastric cancer in American Indian communities.

Assessing Helicobacter pylori and Diet to Develop Cancer Interventions in American Indian Communities in the Southwest

NIH-funded research Fred Hutchinson Cancer Center · NIH-10923901

This study is looking at how stomach infections and eating habits affect the risk of stomach cancer in American Indian communities, especially in the Southwest and Alaska, to find better ways to help people stay healthy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10923901 on NIH RePORTER

What this research studies

This research focuses on understanding how Helicobacter pylori infections and dietary habits contribute to the high rates of gastric cancer among American Indian populations, particularly in the Southwest and Alaska. The study will explore the prevalence of H. pylori and its virulence factors, as well as the impact of diet on gastric health. By leveraging previous experiences with American Indian tribes, the research aims to identify barriers to effective treatment and adherence to therapy. The findings could lead to tailored interventions that address both infection and dietary factors to reduce cancer risk.

Who could benefit from this research

Good fit: Ideal candidates for this research are American Indian individuals, particularly those from the Navajo Nation and other Southwest tribes, who are at risk for gastric cancer due to H. pylori infection.

Not a fit: Patients who do not belong to American Indian communities or who are not at risk for gastric cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies and treatment options for gastric cancer in American Indian communities.

How similar studies have performed: Previous research has shown a correlation between H. pylori infection and gastric cancer, but this specific approach focusing on American Indian populations is novel.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.