Investigating the link between heart tissue changes after a heart attack and dangerous heart rhythms.
LONGITUDINAL ASSOCIATION OF POST-INFARCT LIPOMATOUS METAPLASIA AND MALIGNANT ARRHYTHMIA
This study is looking at how fat buildup in the heart after a heart attack can affect heart rhythms, and it's for patients who have had a heart attack to help understand their heart health better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10981906 on NIH RePORTER |
What this research studies
This research focuses on understanding how changes in heart tissue, specifically fat deposition, occur after a heart attack and how these changes may lead to dangerous heart rhythms. By examining patients who have experienced a myocardial infarction, the study aims to identify the relationship between lipomatous metaplasia and the risk of malignant arrhythmias. The approach includes advanced cardiac imaging and electrophysiological assessments to track these changes over time. Patients will be monitored for heart function and rhythm disturbances, providing valuable insights into their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a myocardial infarction and are at risk for developing arrhythmias.
Not a fit: Patients who have not had a heart attack or do not have any history of cardiac issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing life-threatening heart rhythms in patients who have suffered a heart attack.
How similar studies have performed: Previous studies have shown promising results in understanding the relationship between heart tissue changes and arrhythmias, suggesting that this research builds on established findings.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Nazarian, Saman — University of Pennsylvania
- Study coordinator: Nazarian, Saman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.