Investigating the link between heart disease and retinal artery blockage

Cardioembolism as a Mechanism of Central Retinal Artery Occlusion

NIH-funded research Duke University · NIH-11259280

This study is looking at how a type of eye stroke called central retinal artery occlusion (CRAO) might be linked to heart problems, and it aims to help identify people who are at risk so they can get better care and prevention strategies for their heart health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11259280 on NIH RePORTER

What this research studies

This research focuses on understanding how central retinal artery occlusion (CRAO), a type of stroke affecting the retina, may indicate underlying heart conditions. The study aims to identify specific populations at risk for CRAO and explore its connection to heart issues like atrial fibrillation and heart failure. By analyzing large datasets and patient cohorts, the research seeks to fill gaps in knowledge about CRAO's mechanisms and its implications for future strokes. Patients may be monitored for their heart health and receive personalized prevention strategies based on findings.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced central retinal artery occlusion or are at risk for cerebrovascular disorders.

Not a fit: Patients with retinal artery occlusion due to non-cardiac causes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies for patients at risk of strokes related to heart disease.

How similar studies have performed: Previous research has shown promising results in linking retinal conditions to cardiovascular health, suggesting that this approach may yield valuable insights.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.