Investigating the link between gut bacteria and Alzheimer's disease risk
Official title: Microbiome and AD/ADRD Risk in SOL
Funded at University of Massachusetts Lowell · NIH-11053146 · Data updated 2026-11-12
This study is looking at how the bacteria in our gut might affect the risk of Alzheimer's and related memory issues, especially in Latino communities, to help find new ways to prevent and treat these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Lowell NIH-funded |
| Lab location | 1 site (Lowell, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $856,580 |
| NIH project number | 1R01AG085320-01A1 |
| Project ID | NIH-11053146 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals, particularly Latinos, who are at risk for Alzheimer's disease or related dementias.
✕Less likely to help
Patients who do not have any risk factors for Alzheimer's disease or related dementias may not benefit from this research.
What this research studies
This research explores how the gut microbiome, which interacts with the brain, may influence the risk of Alzheimer's disease and related dementias (AD/ADRD). By studying a diverse group of individuals over a long period, the project aims to identify specific microbial patterns associated with AD/ADRD, particularly in Latino populations who are at higher risk. The researchers will analyze various biological markers and gut microbiome profiles to understand potential connections between diabetes and AD/ADRD. This comprehensive approach could lead to new prevention and treatment strategies based on gut health.
Why it matters
Potential benefit: If successful, this research could lead to innovative strategies for preventing or treating Alzheimer's disease by targeting gut health.
How similar studies have gone: While there have been limited studies on the gut microbiome's role in Alzheimer's disease, this research aims to fill a gap, particularly focusing on Latino populations, making it a novel approach.
Where this research is happening
-
University of Massachusetts Lowell
Lowell, United States Active
Researchers
- Principal investigator: Palacios, Natalia — University of Massachusetts Lowell
- Study coordinator: Palacios, Natalia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.