Investigating the link between gut bacteria and Alzheimer's disease risk
Microbiome and AD/ADRD Risk in SOL
['FUNDING_R01'] · UNIVERSITY OF MASSACHUSETTS LOWELL · NIH-11053146
This study is looking at how the bacteria in our gut might affect the risk of Alzheimer's and related memory issues, especially in Latino communities, to help find new ways to prevent and treat these conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MASSACHUSETTS LOWELL (nih funded) |
| Locations | 1 site (LOWELL, UNITED STATES) |
| Trial ID | NIH-11053146 on ClinicalTrials.gov |
What this research studies
This research explores how the gut microbiome, which interacts with the brain, may influence the risk of Alzheimer's disease and related dementias (AD/ADRD). By studying a diverse group of individuals over a long period, the project aims to identify specific microbial patterns associated with AD/ADRD, particularly in Latino populations who are at higher risk. The researchers will analyze various biological markers and gut microbiome profiles to understand potential connections between diabetes and AD/ADRD. This comprehensive approach could lead to new prevention and treatment strategies based on gut health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals, particularly Latinos, who are at risk for Alzheimer's disease or related dementias.
Not a fit: Patients who do not have any risk factors for Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative strategies for preventing or treating Alzheimer's disease by targeting gut health.
How similar studies have performed: While there have been limited studies on the gut microbiome's role in Alzheimer's disease, this research aims to fill a gap, particularly focusing on Latino populations, making it a novel approach.
Where this research is happening
LOWELL, UNITED STATES
- UNIVERSITY OF MASSACHUSETTS LOWELL — LOWELL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PALACIOS, NATALIA — UNIVERSITY OF MASSACHUSETTS LOWELL
- Study coordinator: PALACIOS, NATALIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia