Investigating the link between fatty liver disease and preeclampsia risk in pregnant women
Nonalcoholic fatty liver disease, associated lipidomic changes, and preeclampsia risk
This study is looking at how nonalcoholic fatty liver disease might increase the chances of developing preeclampsia in overweight and obese pregnant women, with the goal of finding ways to keep moms and babies healthier during pregnancy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11248108 on NIH RePORTER |
What this research studies
This research aims to understand how nonalcoholic fatty liver disease (NAFLD) affects the risk of developing preeclampsia (PE) in overweight and obese pregnant women. The study will assess whether NAFLD is an independent risk factor for PE and will analyze lipid changes in women with NAFLD during pregnancy. By identifying these relationships, the research seeks to develop strategies to reduce the risk of PE and improve maternal health outcomes. The study will take place at the Mount Sinai Health System, which serves a diverse patient population.
Who could benefit from this research
Good fit: Ideal candidates for this research are overweight or obese pregnant women who may have nonalcoholic fatty liver disease.
Not a fit: Patients who are not pregnant or who do not have risk factors for nonalcoholic fatty liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prediction and prevention strategies for preeclampsia, ultimately improving maternal health.
How similar studies have performed: While the specific relationship between NAFLD and preeclampsia is not extensively studied, related research has shown promising results in understanding metabolic conditions during pregnancy.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Kushner, Tatyana — Weill Medical Coll of Cornell Univ
- Study coordinator: Kushner, Tatyana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.